p-Cymene attenuates cancer pain via inhibitory pathways and modulation of calcium currents
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منابع مشابه
Modulation of calcium currents and membrane properties by substance P in the lamprey spinal cord.
Substance P is endogenously released within the locomotor network of the adult lamprey, accelerates the burst frequency of fictive locomotion, and reduces the reciprocal inhibition. Previous studies have shown that dopamine, serotonin, and GABA regulate calcium channels, which control neurotransmitter release, action potential duration, and slow afterhyperpolarization (sAHP). Here we examine th...
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BACKGROUND Crude extracts of Selaginellatamariscina, an oriental medicinal herb, have been evidenced to treat several human diseases. This study investigated the mechanisms by which Selaginellatamariscina inhibits the invasiveness of human oral squamous-cell carcinoma (OSCC) HSC-3 cells. METHODOLOGY/PRINCIPAL FINDINGS Herein, we demonstrate that Selaginellatamariscina attenuated HSC-3 cell mi...
متن کاملModulation of calcium currents and membrane properties by 4 substance P in the lamprey spinal cord
24 25 Substance P is endogenously released within the locomotor network of the adult lamprey, 26 accelerates the burst frequency of fictive locomotion and reduces the reciprocal 27 inhibition. Previous studies have shown that dopamine, 5-HT and GABA regulate 28 calcium channels, which control neurotransmitter release, action potential duration and 29 slow afterhyperpolarization. Here we examine...
متن کاملp-Cymene Promotes Its Catabolism through the p-Cymene and the p-Cumate Pathways, Activates a Stress Response and Reduces the Biofilm Formation in Burkholderia xenovorans LB400
p-Cymene is an aromatic terpene that is present in diverse plant species. The aims of this study were to study the p-cymene metabolism in the model aromatic-degrading bacterium Burkholderia xenovorans LB400, and its response to p-cymene. The catabolic p-cymene (cym) and p-cumate (cmt) genes are clustered on the LB400 major chromosome. B. xenovorans LB400 was able to grow on p-cymene as well as ...
متن کاملModulation of calcium and potassium currents by lamotrigine.
Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and whole cell patch clamp recordings from rat CA1 and CA3 pyramidal cells in vitro. The results suggest that LTG, beside its previously described effect on the fast sodium inward current, also modulates - presumably voltage-gated - calcium currents and the transient potassium outward current ID. Thes...
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ژورنال
عنوان ژورنال: Phytomedicine
سال: 2019
ISSN: 0944-7113
DOI: 10.1016/j.phymed.2019.152836